This is the first time chiropractic research has been published in a journal of such international importance and prestige; Molecular Psychiatry published by Nature.* (Vol. 6 Feb 2001)
The study showed that subluxation correction allows for greater fulfillment of human potential in the area of "state of well-being." The conclusion showed amazing recovery from drug addictions using chiropractic as the main intervention.
According to Dr. Holder, "Neurotransmitters at the limbic system (brain reward cascade) and the dorsal horn of the spinal cord, result in feelings of well-being when operating properly. If an imbalance, such as malfunctioning spine, impedes the normal flow of the cascade, feelings of anxiety, anger, fear or the craving of substances which alleviate negative emotions manifest. Disruption of this brain reward cascade results in Reward Deficiency Syndrome (RDS)."
An instrument was developed by Dr. Holder for the purpose of delivering an adjustment identical to that of the chiropractor's hands. Instead of delivering just axial force, the "Integrator" delivers a third dimension of force; recoil as well as torque, all at the speed of 1/10,000th of a second. This is the instrument used in our office.
In a literature review, Drs. Holder and Blum revealed only vertebrates, (animals w/ a backbone), have an opiate receptor brain reward cascade mechanism. Therefore, in spite of opioid peptides found in invertebrates, only vertebrates express a state of well-being.
In this instance the common denominator is the spine and spinal cord. If the spine is allowed to express itself without interference, the vertebrate, (including us humans!), can express a state of well-being to its greatest potential. This is why people feel so good when they get adjusted regularly!
*Discovery Health Channel aired a documentary in 2002 covering the research.